Selected publications
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Luján* et al. (2024). Dynamic Overrepresentation of Accumbal Cues in Food- and Opioid-Seeking Rats after Prenatal THC Exposure.
–Science Advances 10(45): eadq5652 -
Luján* et al. (2023). Mobilization of endogenous cannabinoids by midbrain dopamine neurons is required for the encoding of predictive reward signals.
–Nature Communications 14: 1-12 -
Luján et al. (2023). A multivariate regressor of patterned dopamine release predicts relapse to cocaine.
–Cell Reports 42(6): 112553
2023
Luján* MÁ, Covey* DP, Young-Morrison R, Zhang LY, Kim A, Morgado F, Patel S, Bass CE, Paladini C, Cheer JF (2023). Mobilization of endogenous cannabinoids by midbrain dopamine neurons is required for the encoding of predictive reward signals. Nature Communications 14: 1-12. *Equally contributed.
Wilkinson CS, Luján MÁ, Hales C, Costa K, Fiore VG, Knackstedt LA, Kober H (2023). Listening to the Data: Computational Approaches to Addiction and Learning. Journal of Neuroscience 43: 7547-7553.
Luján MÁ, Oliver B, Young-Morrison R, Engi S, Zhang LY, Wenzel J, Li Y, Zlebnik N, Cheer JF (2023). A multivariate regressor of patterned dopamine release predicts relapse to cocaine. Cell Reports 42(6): 112553.
2022
Alegre-Zurano L, Berbegal-Sáez P, Luján MÁ, Cantacorps L, Martín‐Sánchez A, García-Baos A, & Valverde O (2022). Cannabidiol decreases motivation for cocaine in a behavioral economics paradigm but does not prevent incubation of craving in mice. Biomedicine & Pharmacotherapy 148: 112708.
2021
Luján MÁ, Cantacorps L, Alegre-Zurano L, Martín‐Sánchez A, & Valverde O (2021). CB1 receptor antagonist AM4113 reverts the effects of cannabidiol on cue and stress-induced reinstatement of cocaine-seeking behaviour in mice. Progress in Neuropsychopharmacology and Biological Psychiatry 113: 110462.
Alegre-Zurano L, López-Arnau R, Luján MÁ, Camarasa J, Valverde O (2021). Cannabidiol modulates the motivational and anxiety-like effects of 3,4-methylenedioxypyrovalerone (MDPV) in mice. International Journal of Molecular Sciences 22(15): 8304.
Covey D, Hernandez E, Luján MÁ, Cheer JF (2021). Enhanced dopaminergic encoding of reward cost and motivation is achieved by chronic augmentation of endocannabinoid levels and is accompanied by a lack of suppression of its effects. Journal of Neuroscience 10: JN-RM-0285-21.
Luján MÁ, Cheer JF, and Melis M (2021). Choosing the right drug: Status and future of endocannabinoid research for the prevention of drug-seeking reinstatement. Current Opinion in Pharmacology 56: 29-38.
2020
Luján* MÁ & Valverde* O (2020) The pro-neurogenic effects of cannabidiol and its potential therapeutic implications in psychiatric disorders. Frontiers in Behavioral Neuroscience, 14, 109. *Corresponding authors.
Cantacorps L, Montagud-Romero S, Luján MÁ, Valverde O. (2020) Prenatal and postnatal alcohol exposure increases vulnerability to cocaine addiction in adult mice. British Journal of Pharmacology 177: 1090-1105.
2019
Castro‐Zavala A, Martín‐Sánchez A, Luján MÁ, Valverde O. (2019). Maternal separation increases cocaine intake through a mechanism involving plasticity in glutamate signalling. Addiction Biology, 26(2): e12911
Luján MÁ, Cantacorps L, & Valverde O (2019) The pharmacological reduction of hippocampal neurogenesis attenuates the protective effects of cannabidiol on cocaine voluntary intake Addiction biology, 25: e12778
Luján MÁ, Colomar L, Tarragón E, López-Cruz L, Pastor R, & Font L (2019) Drug-free and context-dependent locomotor hyperactivity in DBA/2 J mice previously treated with repeated cocaine: Relationship with behavioral sensitization and role of noradrenergic receptors. Pharmacology Biochemistry and Behavior, 176, 101-110
Ferrer-Pérez C, Castro-Zavala A, Luján MÁ, Filarowska J, Ballestín R, Miñarro J, ... & Rodríguez-Arias M (2019). Oxytocin prevents the increase of cocaine-related responses produced by social defeat. Neuropharmacology, 146, 50-64.
2018
Luján MÁ, Castro-Zavala A, Alegre-Zurano L, & Valverde O (2018) Repeated Cannabidiol treatment reduces cocaine intake and modulates neural proliferation and CB1R expression in the mouse hippocampus. Neuropharmacology, 143, 163-175
2017
López-Arnau* R, Luján* MÁ, Duart-Castells L, Pubil, D, Camarasa J, Valverde O and Escubedo E (2017) ‘Exposure of adolescent mice to 3,4-methylenedioxypyrovalerone increases the psychostimulant, rewarding and reinforcing effects of cocaine in adulthood’, British journal of pharmacology, 174: 1161–1173. *Equally contributed.
2013
Font L, Luján MÁ, and Pastor R (2013) ‘Involvement of the endogenous opioid system in the psychopharmacological actions of ethanol: the role of acetaldehyde’ Frontiers in behavioral neuroscience, 7: 93.
2025
Luján MÁ, Young-Morrison R et al., (submitted). Pallid-Tegmental Endocannabinoids Actuate Dopamine-Based Action Selection.
Luján MÁ, Kim A, Zhang LY, Cheer JF (2025). Cannabinoid-based Pharmacology for the Management of Substance Use Disorders. Patel S, Cooper Z (Eds.). In: Current Topics in Behavioral Neurosciences: Behavioral Neurobiology of the Endocannabinoid System (2nd ed.). Springer Nature.
Olusakin J, Dewan M, Kashyap A, Ma DF, Kumar G, Lujan MÁ, Mark KS, Cheer J, & Lobo MK (2025). Concurrent maternal stress and THC exposure during pregnancy alters adolescent behavioral outcomes and corticolimbic molecular programs. BioRxiv, 2025.06.26.661775.
2024
Luján &,* MÁ, Young-Morrison* R, Aroni S, Katona I, Melis M, Cheer JF (2024). Dynamic Overrepresentation of Accumbal Cues in Food- and Opioid-Seeking Rats after Prenatal THC Exposure. Science Advances 10(45): eadq5652. &Corresponding author, *equally contributed.